PXD046781

PXD046781 is an original dataset announced via ProteomeXchange.

Title	From birth to bite: the evolutionary ecology of India's medically most important snake venoms
Description	Venoms of N. naja and D. russelii individuals of various developmental stages, including neonates (<30 days), juveniles (between 1 to 12 months), and mature individuals (>36 months), were sampled with permission from the state forest department of Karnataka. 226 individuals and 9 clutches were examined, including periodic venom collection (every three months) from the same N. naja and D. russelii juvenile individuals to track ontogenetic changes across time. Freshly collected venoms were flash-frozen in liquid nitrogen, lyophilised and stored at -80° C. Venoms were fractionated using RP-HPLC and SDS-PAGE and subjected to tandem mass spectrometry for toxin identification. The relative abundance of each toxin family were estimated and compared across different developmental stages.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:54:22.403.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kartik Sunagar
SpeciesList	scientific name: Naja naja; NCBI TaxID: 35670; scientific name: Daboia russelii; NCBI TaxID: 8707;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-08 04:27:35	ID requested
1	2024-08-10 12:41:34	announced
⏵ 2	2024-10-22 06:54:28	announced	2024-10-22: Updated project metadata.

Senji Laxme RR, Khochare S, Bhatia S, Martin G, Sunagar K, From birth to bite: the evolutionary ecology of India's medically most important snake venoms. BMC Biol, 22(1):161(2024) [pubmed]

10.1186/s12915-024-01960-8;

submitter keyword: Thermofisher orbitrap fusion mass spectrometry, snake venom,Daboia russelii, venom proteomics, Naja naja, ontogeny

Dr Kartik
contact affiliation	Assistant Professor and Group Leader, Indian institute of Science (IISc), Bangalore
contact email	ksunagar@iisc.ac.in
lab head
Kartik Sunagar
contact affiliation	Assistant Professor, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India.
contact email	ksunagar@iisc.ac.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD046781

PRIDE project URI

• PRIDE
  1. PXD046781
     1. Label: PRIDE project
     2. Name: From birth to bite: the evolutionary ecology of India's medically most important snake venoms