PXD046760

PXD046760 is an original dataset announced via ProteomeXchange.

Title	SILAC-based quantitative proteomics using mass spectrometry identifies BAG-6 mediated changes in the subproteome degraded by endosomal microautophagy (eMI).
Description	To identify the subproteome degraded by endosomal microautophagy (eMI) in a Bag6-dependent manner, we compared the proteome of late endosomal compartments LE/MVBs isolated from control(wild type) and Bag6(-) cells using SILAC labeling and quantitative proteomics.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:25:45.306.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD046760
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Cristina Clement
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	6x(13)C labeled residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-07 15:09:15	ID requested
1	2024-01-26 07:05:56	announced
⏵ 2	2024-10-22 06:25:50	announced	2024-10-22: Updated project metadata.

10.6019/PXD046760;

10.1016/j.celrep.2023.113529;

Krause GJ, Kirchner P, Stiller B, Morozova K, Diaz A, Chen KH, Krogan NJ, Agullo-Pascual E, Clement CC, Lindenau K, Swaney DL, Dilipkumar S, Bravo-Cordero JJ, Santambrogio L, Cuervo AM, Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy. Cell Rep, 42(12):113529(2023) [pubmed]

submitter keyword: mouse JAWS, BAG-6 KO, late endosomes

Anna-Maria Cuervo
contact affiliation	Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
contact email	ana-maria.cuervo@einsteinmed.edu
lab head
Cristina Clement
contact affiliation	Weill Cornell Medicine
contact email	ccc4002@med.cornell.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD046760

PRIDE project URI

• PRIDE
  1. PXD046760
     1. Label: PRIDE project
     2. Name: SILAC-based quantitative proteomics using mass spectrometry identifies BAG-6 mediated changes in the subproteome degraded by endosomal microautophagy (eMI).