PXD046730

PXD046730 is an original dataset announced via ProteomeXchange.

Title	Proteome-wide analysis of S. cerevisiae controlled by the optogenetic cell cycle regulator bPAC (photo activatable adenylate cyclase from Beggiatoa)
Description	The field of optogenetics offers a powerful toolbox to control cellular processes. We used the photo activatable adenylate cyclase from Beggiatoa to restrict cell-cycle progression under specific light conditions. In a label-free proteomics experiment we investigated the influence of cell-cycle restriction on the proteome, comparing cells grown under restrictive/permissive light conditions and wild-type cells.
HostingRepository	PRIDE
AnnounceDate	2026-04-24
AnnouncementXML	Submission_2026-04-24_11:50:42.049.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD046730
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Christof Taxis
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: NEWT:4932;
ModificationList	carbamoylated residue; phosphorylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-07 01:03:34	ID requested
⏵ 1	2026-04-24 11:50:42	announced

10.1128/AEM.02498-25;

10.6019/PXD046730;

submitter keyword: yeast light control degradation

Lars-Oliver Essen
contact affiliation	Philipps-Universität Marburg, Fachbereich Chemie, Biochemie/Strukturbiologie
contact email	essenl@staff.uni-marburg.de
lab head
Christof Taxis
contact affiliation	Health and Medical University Erfurt
contact email	christof.taxis@health-and-medical-university.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD046730

PRIDE project URI

• PRIDE
  1. PXD046730
     1. Label: PRIDE project
     2. Name: Proteome-wide analysis of S. cerevisiae controlled by the optogenetic cell cycle regulator bPAC (photo activatable adenylate cyclase from Beggiatoa)