PXD046649

PXD046649 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Simultaneous proteome localization and turnover analysis, Rep. 3
Description	To examine the protein spatial and temporal changes upon carfilzomib-mediated proteasome inhibition in cardiac cells, we produced human iPSC-derived cardiomyocytes using a standard small molecule based protocol. Cardiomyocyte identity was confirmed by morphology, observation of contraction, and the presence of GFP tagged MLC-2a in the reporter line. We then applied the SPLAT protocol to untreated and carfilzomib-exposed iPSC-cardiomyocytes.
HostingRepository	jPOST
AnnounceDate	2023-11-03
AnnouncementXML	Submission_2023-11-03_09:29:12.624.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sean Robinson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex reporter+balance reagent N-acylated residue; TMT6plex reporter+balance reagent acylated N-terminal; Label:13C(6)15N(2); Label:13C(6)15N(4)
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-03 09:24:57	ID requested
⏵ 1	2023-11-03 09:29:13	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Human, AC16, TMT, TMT10, Spatiotemporal

submitter keyword: Human, AC16, TMT, TMT10, Spatiotemporal

Contact List

Dr. Edward Lau
lab head
Sean Robinson
contact affiliation	University of Colorado, Anschutz Medical Campus
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002376/