PXD046614 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Off-target profiling of Olaparib using Thermal Proteome Profiling |
Description | Explore off-targets of Olaparib using 2D Thermal Proteome Profiling (2D-TPP) |
HostingRepository | PRIDE |
AnnounceDate | 2024-05-13 |
AnnouncementXML | Submission_2024-05-13_03:10:49.237.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Maria Faelth Savitski |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; methionine oxidation with neutral loss of 64 Da; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-11-02 11:15:37 | ID requested | |
⏵ 1 | 2024-05-13 03:10:50 | announced | |
Publication List
10.1038/s44320-024-00025-w; |
Burtscher ML, Gade S, Garrido-Rodriguez M, Rutkowska A, Werner T, Eberl HC, Petretich M, Knopf N, Zirngibl K, Grandi P, Bergamini G, Bantscheff M, F, รค, lth-Savitski M, Saez-Rodriguez J, Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Mol Syst Biol, 20(4):458-474(2024) [pubmed] |
Keyword List
submitter keyword: thermal proteome profiling, PARP,2D-TPP, Olaparib |
Contact List
Marcus Bantscheff |
contact affiliation | Cellzome |
contact email | marcus.x.bantscheff@gsk.com |
lab head | |
Maria Faelth Savitski |
contact affiliation | Cellzome |
contact email | maria.x.faelth-savitski@gsk.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD046614 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046614
- Label: PRIDE project
- Name: Off-target profiling of Olaparib using Thermal Proteome Profiling