⮝ Full datasets listing
PXD046586
PXD046586 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Integrated Proteomics Identifies Troponin I Isoform Switch as a Regulator of a Sarcomere-Metabolism Axis During Cardiac Regeneration |
| Description | Raw files, diaNN search results, and R script. 75 mouse heart samples from WT and Tnni1 Tg mice for global bottom-up proteomics of cardiac development, injury, and regeneration (diaPASEF). 75 mouse heart samples from WT and Tnni1 Tg mice for targeted top-down proteomics of the cardiac sarcomere during cardiac development, injury, and regeneration |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-08-03 |
| AnnouncementXML | Submission_2026-08-03_10:54:11.876.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Timothy Aballo |
| SpeciesList | scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro; impact II |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-11-01 09:18:30 | ID requested | |
| ⏵ 1 | 2026-08-03 10:54:13 | announced |
Publication List
| Aballo TJ, Bae J, Paltzer WG, Chapman EA, Perciaccante AJ, Pergande MR, Salamon RJ, Nuttall DJ, Mann MW, Ge Y, Mahmoud AI, Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration. Cardiovasc Res, 121(8):1240-1253(2025) [pubmed] |
Keyword List
| submitter keyword: top-down proteomics, bottom-up proteomics, cardiac regeneration |
Contact List
| Ying Ge | |
|---|---|
| contact affiliation | University of Wisconsin-Madison |
| contact email | ge2@wisc.edu |
| lab head | |
| Ahmed I. Mahmoud | |
| contact affiliation | University of Wisconsin-Madison |
| contact email | aimahmoud@wisc.edu |
| lab head | |
| Timothy Aballo | |
| contact affiliation | University of Wisconsin-Madison |
| contact email | aballo@wisc.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v06/MSV000093225/ |
