PXD046557
PXD046557 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | An E3 ligase TRIM1 promotes colorectal cancer progression via K63-linked ubiquitination and activation of HIF1α |
| Description | We determined the binding and ubiquitination of HIF1a by an E3 ligase TRIM1. IP experiments were performed from SW480 cells and Ms files were acquired on Q Exactive mass spectrometer. We analysed the differences of protein abundance, comparing the normalized intensity on distinct proteins from different groups. |
| HostingRepository | iProX |
| AnnounceDate | 2024-02-22 |
| AnnouncementXML | Submission_2024-10-17_20:32:01.894.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kun Meng |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | ubiquitination signature dipeptidyl lysine |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-10-31 19:45:42 | ID requested | |
| 1 | 2023-10-31 19:45:56 | announced | |
| ⏵ 2 | 2024-10-17 20:32:02 | announced | 2024-10-18: Update information. |
Publication List
| Shi L, Fang X, Du L, Yang J, Xue J, Yue X, Xie D, Hui Y, Meng K, . Oncogenesis, 13(1):16(2024) [pubmed] |
Keyword List
| submitter keyword: ubiquitination, HIF1α |
Contact List
| Kun Meng | |
|---|---|
| contact affiliation | Taihe Hospital, Hubei University of Medicine |
| contact email | 15896536298@163.com |
| lab head | |
| Kun Meng | |
| contact affiliation | Taihe Hospital, Hubei University of Medicine |
| contact email | 15896536298@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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