PXD046502 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Palmitate suppresses CD8+ T cell antitumoral response by disrupting mitochondrial metabolism |
| Description | Accumulation of lipids in the tumor microenvironment (TME) is a feature of several solid tumors and increased palmitate (PA) availability fosters tumor progression and metastases. The intrinsic effects of PA on cancer cells are well understood, but its role in modulating CD8+ T cells (CTL) functional performances remains poorly understood. Here, we analyzed histone PTM levels in CTLs in response to PA treatment. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-20 |
| AnnouncementXML | Submission_2026-02-20_09:10:53.683.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Roberta Noberini |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | monomethylated residue; trimethylated residue; acetylated residue; dimethylated residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-10-30 06:31:41 | ID requested | |
| ⏵ 1 | 2026-02-20 09:10:54 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: histone post-translational modifications, acetylation |
Contact List
| Tiziana Bonaldi |
|---|
| contact affiliation | European Institute of Oncology, Milan |
| contact email | tiziana.bonaldi@ieo.it |
| lab head | |
| Roberta Noberini |
|---|
| contact affiliation | Istituto Europeo di Oncologia |
| contact email | roberta.noberini@ieo.it |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046502
- Label: PRIDE project
- Name: Palmitate suppresses CD8+ T cell antitumoral response by disrupting mitochondrial metabolism
