PXD046393

PXD046393 is an original dataset announced via ProteomeXchange.

Title	Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds
Description	Effects to protein homeostasis processes upon treatment with cysteine-reactive covalent small molecules in viral and host proteins
HostingRepository	PRIDE
AnnounceDate	2024-10-24
AnnouncementXML	Submission_2024-10-24_13:12:32.337.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Flowreen Shikwana
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-25 09:26:42	ID requested
⏵ 1	2024-10-24 13:12:32	announced

10.1038/S41589-024-01760-9;

submitter keyword: SARS-CoV-2, covalent compounds, protein degradation,Cysteine-reactive elecrophiles, aggregation

Keriann Marie Backus
contact affiliation	Biological Chemistry, UCLA, United States
contact email	kbackus@mednet.ucla.edu
lab head
Flowreen Shikwana
contact affiliation	UCLA
contact email	flowreen.shikwana@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD046393

PRIDE project URI

• PRIDE
  1. PXD046393
     1. Label: PRIDE project
     2. Name: Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds