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PXD046278

PXD046278 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds
DescriptionisoTOP-ABPP performed for a small library of cysteine-reactive compounds to assess cysteine ligandability of viral and host proteins towards these compounds.
HostingRepositoryPRIDE
AnnounceDate2024-10-24
AnnouncementXMLSubmission_2024-10-24_12:51:00.403.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFlowreen Shikwana
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListbiotinylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-20 21:05:59ID requested
12024-10-24 12:51:00announced
Publication List
10.1038/S41589-024-01760-9;
Keyword List
submitter keyword: isoTOP-ABPP
SARS-CoV-2
cysteine-reactive compounds
proteostasis
Orbitrap Eclipse: SP3
FAIMS
Contact List
Keriann Marie Backus
contact affiliationBiological Chemistry, UCLA, United States
contact emailkbackus@mednet.ucla.edu
lab head
Flowreen Shikwana
contact affiliationUCLA
contact emailflowreen.shikwana@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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