PXD046259
PXD046259 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Ejection of mitochondria and TNF-α activation mediate hypertonicity-induced adipocytes dedifferentiation |
Description | Adipocyte extracellular vesicles and particles (EVs) proteomic profiling. In this study, we focus on the EVs proteomes changes induced by hypertonicity in 3T3-L1 and differentiated adipocytes. The source cells were cultured with isotonic/hypertonic medium for 48 hours, and EVs were isolated from the conditional medium using sequential ultracentrifugation. A label-free MS strategy was employed to achieve proteome identification and quantification. |
HostingRepository | iProX |
AnnounceDate | 2023-10-20 |
AnnouncementXML | Submission_2024-02-22_19:51:08.559.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Liang Zhang |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-10-20 05:00:24 | ID requested | |
1 | 2023-10-20 05:02:18 | announced | |
⏵ 2 | 2024-02-22 19:51:09 | announced | 2024-02-23: Update information. |
Publication List
Liu G, Wang Y, Pan Y, Tian L, Choi MH, Wang L, Kim JY, Zhang J, Cheng SH, Zhang L, -catenin signaling to promote adipocyte dedifferentiation. Stem Cell Res Ther, 14(1):333(2023) [pubmed] |
Keyword List
submitter keyword: adipocyte, hypertonicity, EVs, mitochondria |
Contact List
Liang Zhang | |
---|---|
contact affiliation | City Univeristy of Hong Kong |
contact email | liangzhang.28@cityu.edu.hk |
lab head | |
Liang Zhang | |
contact affiliation | City University of Hong Kong |
contact email | liangzhang.28@cityu.edu.hk |
dataset submitter |
Full Dataset Link List
iProX dataset URI |