PXD046209
PXD046209 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | EttA alleviates early ribosome stalling events induced by acidic residues |
| Description | In this study we have used an unbiased approach to determine the impact of the ettA deletion (delta ettA) on the physiology of E. coli. The gene deletion creates a hypersensitivity to salt when the bacteria are grown on carbon sources metabolized by the TCA cycle. This phenotype is due to the reduced translation of several genes of the TCA cycle and of genes involved in stress responses. In this work we have systematically compared three strains MG1655 WT, delta ettA and the delta ettA complemented with an exogenous chromosomal copy of ettA (CettA). Label-Free mass spectrometry studies performed on light (S15) and heavy (S150) fractions of proteins extracts from cultures grown in MMAA-NaCl medium, identified several protein expression changes in the delta ettA strain compared to the WT or the CettA strains. |
| HostingRepository | MassIVE |
| AnnounceDate | 2024-06-24 |
| AnnouncementXML | Submission_2024-06-25_00:45:39.930.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hamon |
| SpeciesList | scientific name: Escherichia coli; common name: E. coli; NCBI TaxID: 562; |
| ModificationList | L-methionine sulfoxide; Acetyl; Carbamidomethyl |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-10-18 08:04:18 | ID requested | |
| ⏵ 1 | 2024-06-25 00:45:40 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: ABC-F protein family, quantification, label-free, mass spectrometry |
Contact List
| Gregory Boel | |
|---|---|
| contact affiliation | UMR 8261, IBPC, CNRS |
| contact email | Boel@ibpc.fr |
| lab head | |
| Hamon | |
| contact affiliation | IBPC-CNRS |
| contact email | marion.hamon@ibpc.fr |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093143/ |
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