PXD046207

PXD046207 is an original dataset announced via ProteomeXchange.

Title	TMT-based proteomics analysis of optic nerve lysates from oligodendrocyte-specific Kir4.1 knockout mice
Description	To study the role oligodendroglial Kir4.1 in regulating axonal energy metabolism, oligodendrocyte-specific Kir4.1 knockout mice and their littermate controls were used; optic nerve lysates were prepared for subsequent TMT-based proteomics.
HostingRepository	PRIDE
AnnounceDate	2024-01-30
AnnouncementXML	Submission_2024-01-30_08:43:44.941.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aiman Saab
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-18 05:48:05	ID requested
⏵ 1	2024-01-30 08:43:45	announced

10.1038/S41593-023-01558-3;

submitter keyword: LC-MSMS,Mouse, TMT proteomics, optic nerve, oligodendrocytes, Kir4.1 knockout

Aiman Saab
contact affiliation	Institute of Pharmacology and Toxicology, University of Zurich, Switzerland
contact email	asaab@pharma.uzh.ch
lab head
Aiman Saab
contact affiliation	University of Zurich, Institute of Pharmacology & Toxicology
contact email	asaab@pharma.uzh.ch
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD046207
     1. Label: PRIDE project
     2. Name: TMT-based proteomics analysis of optic nerve lysates from oligodendrocyte-specific Kir4.1 knockout mice