PXD046203

PXD046203 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	quantitative proteomics analysis of Styxl1-/- mouse sperm
Description	In order to investigate the molecular mechanism of Styxl1 in the regulation of sperm flagella, sperm from Styxl1+/+ and Styxl1-/- mice were collected for quantitative proteomics analysis using TMT-based liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach. A total of 6429 proteins were quantified, and 1517 proteins (p < 0.05, Foldchange > 2) were differentially expressed. Among these differential proteins, 986 proteins were downregulated (65%) and 531 proteins were upregulated (35%) in Styxl1-/- sperm.
HostingRepository	PRIDE
AnnounceDate	2023-12-01
AnnouncementXML	Submission_2023-12-01_08:57:13.984.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yueshuai Guo
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-18 00:44:20	ID requested
⏵ 1	2023-12-01 08:57:14	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Styxl1, Sperm,Quantitative proteomics, TMT, Mouse

submitter keyword: Styxl1, Sperm,Quantitative proteomics, TMT, Mouse

Contact List

Xuejiang Guo
contact affiliation	State Key Laboratory of Reproductive Medicine and Offspring Health,Nanjing Medical University
contact email	guo_xuejiang@njmu.edu.cn
lab head
Yueshuai Guo
contact affiliation	Nanjing Medical University
contact email	gys_706@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD046203
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD046203

PRIDE project URI

Repository Record List

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