PXD046176

PXD046176 is an original dataset announced via ProteomeXchange.

Title	[HPP-2.0] The Comparable Microenvironment Shared by Colorectal Adenoma and Carcinoma: An Evidence of Stromal Proteomics
Description	we initiated a proteomic project to survey stromal proteins responsive to adenoma and carcinoma of colorectal tissues. Most tissues of adjacent, adenoma, and carcinoma were individually sampled from CRC patients using LCM, after which tissue samples were subjected to proteomic analysis using high-resolution mass spectrometry and individual quantification in data-independent acquisition (DIA) mode. By integrating various datasets and bioinformatic algorithms, the analysis concluded that the epithelial proteomics were CRC stage-dependent, whereas the stromal proteomics in adenoma was comparable with that in carcinoma.
HostingRepository	iProX
AnnounceDate	2023-10-17
AnnouncementXML	Submission_2023-10-17_00:47:55.245.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Siqi Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-17 00:47:41	ID requested
⏵ 1	2023-10-17 00:47:56	announced

Yan K, Bai B, Ren Y, Cheng B, Zhang X, Zhou H, Liang Y, Chen L, Zi J, Yang Q, Zhao Q, Liu S, The Comparable Microenvironment Shared by Colorectal Adenoma and Carcinoma: An Evidence of Stromal Proteomics. Front Oncol, 12():848782(2022) [pubmed]

submitter keyword: Colorectal Adenoma and Carcinoma, LC-MS/MS, proteomics

Jin Zi
contact affiliation	Beijing Genomics Institute-Shenzhen
contact email	zij@bgi.com
lab head
Siqi Li
contact affiliation	Beijing Genomics Institute-Shenzhen
contact email	lisiqi@genomics.cn
dataset submitter

iProX dataset URI