PXD046121

PXD046121 is an original dataset announced via ProteomeXchange.

Title	Changes in the urinary proteome of rats after short-term intake of minerals
Description	Magnesium is an important mineral in living organisms and has multiple functions in the human body, wherein it plays an important therapeutic and preventive role in a variety of diseases. In the present study, urine samples of rats before and after gavage of magnesium threonate were collected, and the urinary proteome was identified using the LC-MS/MS technique and analyzed using various databases. The results illustrated that the urinary proteome of rats was significantly altered after short-term intake of magnesium supplements and that the differential proteins and the biological functions were related to magnesium. This study innovatively establishes a method to study nutrients from the perspective of urine proteomics. This work demonstrates that the urinary proteome is capable of reflecting the effects of nutrient intake on the organism in a more systematic and comprehensive manner and has the potential to provide clues for clinical nutrition research and practice.
HostingRepository	iProX
AnnounceDate	2023-10-13
AnnouncementXML	Submission_2024-02-19_19:29:11.992.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ziyun Shen
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-13 06:24:19	ID requested
1	2023-10-13 06:24:34	announced
⏵ 2	2024-02-19 19:29:12	announced	2024-02-20: Update publication

Shen Z, Yang M, Wang H, Liu Y, Gao Y, Changes in the urinary proteome of rats after short-term intake of magnesium L-threonate(MgT). Front Nutr, 10():1305738(2023) [pubmed]

submitter keyword: urine, proteomic, magnesium, nutrients, mineral elements

Youhe Gao
contact affiliation	Beijing Normal University
contact email	gaoyouhe@bnu.edu.cn
lab head
Ziyun Shen
contact affiliation	Beijing Normal University
contact email	202121200043@mail.bnu.edu.cn
dataset submitter

iProX dataset URI