PXD046088
PXD046088 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SaLT&PepPr is an Interface-Predicting Language Model for Designing Peptide-Guided Protein Degraders |
| Description | Cell lysates were adjusted to 5% SDS, and 20 ugs was reduced with 10 mM DTT and alkylated with 25 mM iodoacetamide followed by digestion with 1:15 trypsin using an S-trap at 47 degC for 1 h. Lyophilized peptides were reconstituted at 0.5 ugs/uL, and a study pool QC sample was made by mixing equal volumes of all samples. 1.75 uL of each sample was analyzed once, interspersed with 3 replicates of the SPQC pool, using a Waters M-Class in trap-elute configuration (75 uM x 25 cm HSS-T3 analytical column at 400 nl/min, 5-30% MeCN over 90 min) interfaced to a Thermo Exploris 480 with staggered overlapping window DIA MS analysis. Raw files were deconvoluted with .HTRMS converter (Biognosys) followed by direct-DIA and peptide/protein quantification with Spectronaut 16 (Biognosys). |
| HostingRepository | MassIVE |
| AnnounceDate | 2023-10-13 |
| AnnouncementXML | Submission_2023-10-13_13:22:22.595.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Matt Foster |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Carbamidomethyl |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-10-12 06:44:08 | ID requested | |
| ⏵ 1 | 2023-10-13 13:22:22 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: data-independent analysis |
Contact List
| Pranam Chatterjee | |
|---|---|
| contact affiliation | Duke University |
| contact email | pranam.chatterjee@duke.edu |
| lab head | |
| Matt Foster | |
| contact affiliation | Duke University |
| contact email | mwfoster@duke.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000093088/ |
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