PXD046046
PXD046046 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic and glycoproteomic analysis of iCCA cells |
Description | Utilizing our proteogenomic resources from a cohort of 262 iCCA patients (Cancer Cell. 40(1):70-87 e15), we identified ST3GAL1 as a prognostically relevant molecule in iCCA. Moreover, overexpression of ST3GAL1 promoted proliferation, migration and invasion and inhibited apoptosis of iCCA cells in vitro. We identified the proteins and the O-glycosylation that ST3GAL1 may regulate and identified downstream pathways through proteomic and glycoproteomic analysis |
HostingRepository | iProX |
AnnounceDate | 2024-06-17 |
AnnouncementXML | Submission_2024-07-25_19:34:37.593.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hua Fang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-10-10 19:51:15 | ID requested | |
⏵ 1 | 2024-07-25 19:34:38 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Proteomics, glycoproteomics,protein, O-glycosylation, LC-MS/MS |
Contact List
Shu Zhang | |
---|---|
contact affiliation | Zhongshan hospital of Fudan University |
contact email | zhangshu@fudan.edu.cn |
lab head | |
Hua Fang | |
contact affiliation | Fudan University |
contact email | fhchen23@m.fudan.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |