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PXD046046

PXD046046 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic and glycoproteomic analysis of iCCA cells
DescriptionUtilizing our proteogenomic resources from a cohort of 262 iCCA patients (Cancer Cell. 40(1):70-87 e15), we identified ST3GAL1 as a prognostically relevant molecule in iCCA. Moreover, overexpression of ST3GAL1 promoted proliferation, migration and invasion and inhibited apoptosis of iCCA cells in vitro. We identified the proteins and the O-glycosylation that ST3GAL1 may regulate and identified downstream pathways through proteomic and glycoproteomic analysis
HostingRepositoryiProX
AnnounceDate2024-06-17
AnnouncementXMLSubmission_2024-07-25_19:34:37.593.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHua Fang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-10 19:51:15ID requested
12024-07-25 19:34:38announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Proteomics, glycoproteomics,protein, O-glycosylation, LC-MS/MS
Contact List
Shu Zhang
contact affiliationZhongshan hospital of Fudan University
contact emailzhangshu@fudan.edu.cn
lab head
Hua Fang
contact affiliationFudan University
contact emailfhchen23@m.fudan.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI