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PXD046045

PXD046045 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome analysis of Alpine Merino sheep skin reveals new insights into the mechanisms involved in regulating wool fiber diameter
DescriptionWool fiber is a textile material that is highly valued based on its diameter, which is crucial in de-termining its economic value. To analyze the molecular mechanisms regulating wool fiber diameter, we used a data-independent acquisition-based quantitative proteomics approach to analyze the skin proteome of Alpine Merino sheep with four fiber diameter ranges. From three comparison group, we identified 275, 229, and 190 differentially expressed proteins (DEPs), Further analysis using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways re-vealed that pathways associated with cyclic adenosine monophosphate and peroxisome prolifer-ator-activated receptor signaling are relevant to wool fiber diameter.
HostingRepositoryiProX
AnnounceDate2023-10-11
AnnouncementXMLSubmission_2024-03-20_00:15:48.688.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLin Yue
SpeciesList scientific name: Ovis aries; NCBI TaxID: 9940;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-10 19:49:18ID requested
12024-03-20 00:15:50announced
Publication List
Yue L, Lu Z, Guo T, Liu J, Yang B, Yuan C, Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter. Int J Mol Sci, 24(20):(2023) [pubmed]
Keyword List
submitter keyword: Alpine Merino sheep, proteomics, wool fiber diameter, WGCNA
Contact List
Chao Yuan
contact affiliationLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences
contact emailyuanchao@caas.cn
lab head
Lin Yue
contact affiliationLanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences
contact emailyuel_199804@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI