PXD046045
PXD046045 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome analysis of Alpine Merino sheep skin reveals new insights into the mechanisms involved in regulating wool fiber diameter |
| Description | Wool fiber is a textile material that is highly valued based on its diameter, which is crucial in de-termining its economic value. To analyze the molecular mechanisms regulating wool fiber diameter, we used a data-independent acquisition-based quantitative proteomics approach to analyze the skin proteome of Alpine Merino sheep with four fiber diameter ranges. From three comparison group, we identified 275, 229, and 190 differentially expressed proteins (DEPs), Further analysis using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways re-vealed that pathways associated with cyclic adenosine monophosphate and peroxisome prolifer-ator-activated receptor signaling are relevant to wool fiber diameter. |
| HostingRepository | iProX |
| AnnounceDate | 2023-10-11 |
| AnnouncementXML | Submission_2024-03-20_00:15:48.688.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lin Yue |
| SpeciesList | scientific name: Ovis aries; NCBI TaxID: 9940; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-10-10 19:49:18 | ID requested | |
| ⏵ 1 | 2024-03-20 00:15:50 | announced |
Publication List
| Yue L, Lu Z, Guo T, Liu J, Yang B, Yuan C, Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter. Int J Mol Sci, 24(20):(2023) [pubmed] |
Keyword List
| submitter keyword: Alpine Merino sheep, proteomics, wool fiber diameter, WGCNA |
Contact List
| Chao Yuan | |
|---|---|
| contact affiliation | Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences |
| contact email | yuanchao@caas.cn |
| lab head | |
| Lin Yue | |
| contact affiliation | Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences |
| contact email | yuel_199804@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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