PXD045985

PXD045985 is an original dataset announced via ProteomeXchange.

Title	Identification of proteins that interact with the latch domain of BAK
Description	Previous results show that the latch domain of BAK is able to trigger an autophagic response that has atypical features. Identification of a mutant form that lacks the activity (including 5 mutations, 5M version) allowed the design of a proteomics project directed to find proteins that specifically bind the WT version of the domain but not the mutant form. These proteins would be good candidates to constitute proximal signaling machinery used by the latch domain to activate the autophagic signaling pathway.
HostingRepository	PRIDE
AnnounceDate	2025-03-10
AnnouncementXML	Submission_2025-03-10_05:57:56.401.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD045985
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Felipe X Pimentel-Muinos
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-09 04:50:08	ID requested
⏵ 1	2025-03-10 05:57:56	announced

10.6019/PXD045985;

submitter keyword: autophagy, apoptosis,BAK

Felipe Xosé Pimentel
contact affiliation	Centro de Biología Molecular Severo Ochoa (CBMSO). CSIC-UAM. Nicolas Cabrera, 1. 28049, Madrid. Spain.
contact email	fxp@cbm.csic.es
lab head
Felipe X Pimentel-Muinos
contact affiliation	Centro de Biologia Molecular Severo Ochoa (CSIC-UAM). Consejo Superior de Investigaciones Cientificas. Universidad Autonoma de Madrid. Nicolas Cabrera, 1. Madrid, 28049
contact email	fxp@usal.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD045985

PRIDE project URI

• PRIDE
  1. PXD045985
     1. Label: PRIDE project
     2. Name: Identification of proteins that interact with the latch domain of BAK