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PXD045973

PXD045973 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic investigation on the direct corona of nanoparticles
DescriptionThe application of nanotechnology to medicine has gained wide attention in numerous important scientific fields, ranging from diagnostic imaging with contrast agents to targeted drug delivery and photodynamic therapy.However, upon contact with biological fluid, these GNPs are coated with a layer/corona of proteins that leads to unexpected changes in cellular uptake, cellular interactions, biodistribution, and nanotoxicity. Therefore, detailed knowledge of the protein corona is of importance for the designation and development of nanoparticles with high targeting effect.
HostingRepositoryiProX
AnnounceDate2023-10-08
AnnouncementXMLSubmission_2023-10-08_19:49:17.008.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJian Zhou
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue; monohydroxylated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-08 19:49:07ID requested
12023-10-08 19:49:17announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: nanoparticle, protein corona, proteomics, mass spectrometry
Contact List
Jian Zhou
contact affiliationChongqing Medical University
contact emailzhoujian@cqmu.edu.cn
lab head
Jian Zhou
contact affiliationChongqing Medical University
contact emailzhoujian@cqmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI