PXD045888

PXD045888 is an original dataset announced via ProteomeXchange.

Title	Dynamic proximity based interactome of the transcription factor RELA to identify gene-regulatory networks revealed
Description	Using p65-miniTurbo fusion proteins in HeLa cells, we identified by biotin tagging > 350 RELA interactors from untreated and IL-1a-stimulated cells, including many TFs (47 % of all interactors) and > 50 epigenetic regulators belonging to different classes of chromatin remodeling complexes.
HostingRepository	PRIDE
AnnounceDate	2024-11-04
AnnouncementXML	Submission_2024-11-04_08:46:23.246.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Axel Weber
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-03 18:48:52	ID requested
⏵ 1	2024-11-04 08:46:23	announced

Dataset with its publication pending

submitter keyword: LC-MSMS, RELA, affinity proteomics, Turbo ID, genetic networks,p65 NF-kB, interactome

Michael Kracht
contact affiliation	Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, D-35392, Germany
contact email	michael.kracht@pharma.med.uni-giessen.de
lab head
Axel Weber
contact affiliation	Rudolf-Buchheim-Institute of Pharmacology Justus Liebig University Gießen
contact email	axel.weber@pharma.med.uni-giessen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/11/PXD045888

PRIDE project URI

• PRIDE
  1. PXD045888
     1. Label: PRIDE project
     2. Name: Dynamic proximity based interactome of the transcription factor RELA to identify gene-regulatory networks revealed