PXD045858 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Stoichiometric and structural analyses support the 48:12 model of the human pyruvate dehydrogenase complex core |
| Description | Chemical cross-linking coupled to mass spectrometry using the amine-reactive BS3 reagent was used to study the organization of the human pyruvate dehydrogenase complex core consisting of multiple copies of dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase-binding protein (E3BP) assembled into a 60-mer complex. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-05-15 |
| AnnouncementXML | Submission_2024-05-15_03:10:43.772.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Alexander Leitner |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2023-10-02 08:13:05 | ID requested | |
| ⏵ 1 | 2024-05-15 03:10:44 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Chemical cross-linking |
| BS3 |
| structural proteomics |
| pyruvate dehydrogenase |
Contact List
| Alexander Leitner |
| contact affiliation | ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland |
| contact email | leitner@imsb.biol.ethz.ch |
| lab head | |
| Alexander Leitner |
| contact affiliation | ETH Zurich, Institute of Molecular Systems Biology |
| contact email | leitner@imsb.biol.ethz.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD045858 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD045858
- Label: PRIDE project
- Name: Stoichiometric and structural analyses support the 48:12 model of the human pyruvate dehydrogenase complex core