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PXD045858

PXD045858 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleStoichiometric and structural analyses support the 48:12 model of the human pyruvate dehydrogenase complex core
DescriptionChemical cross-linking coupled to mass spectrometry using the amine-reactive BS3 reagent was used to study the organization of the human pyruvate dehydrogenase complex core consisting of multiple copies of dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase-binding protein (E3BP) assembled into a 60-mer complex.
HostingRepositoryPRIDE
AnnounceDate2024-05-15
AnnouncementXMLSubmission_2024-05-15_03:10:43.772.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlexander Leitner
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-02 08:13:05ID requested
12024-05-15 03:10:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Chemical cross-linking
BS3
structural proteomics
pyruvate dehydrogenase
Contact List
Alexander Leitner
contact affiliationETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland
contact emailleitner@imsb.biol.ethz.ch
lab head
Alexander Leitner
contact affiliationETH Zurich, Institute of Molecular Systems Biology
contact emailleitner@imsb.biol.ethz.ch
dataset submitter
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Dataset FTP location
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PRIDE project URI
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