PXD045798

PXD045798 is an original dataset announced via ProteomeXchange.

Title	Secreted and surface proteome and transcriptome of Opisthorchis felineus
Description	Opisthorchis felineus is one of the three most medically important species belonging to the family of fish-borne zoonotic trematodes known as Opisthorchiidae. O. felineus is endemic to the river plains of Western Siberia and Eastern Europe and it is estimated that more than 1.6 million people could be infected with this parasite. To aid in the development of better control and diagnosis strategies for opisthorchiasis, we set out to deduce the secreted proteome of O. felineus. Adult flukes were collected from experimentally infected hamsters and cultured in vitro in serum-free media. We extracted proteins from different compartments of the O. felineus secretome, including (i) soluble excretory/secretory (ES) products; (ii) secreted microvesicles (MVs); and (iii) tegument. The tegument was further separated into three fractions of varying solubility via sequential extraction.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:55:05.881.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Javier Sotillo
SpeciesList	scientific name: Opisthorchis felineus; NCBI TaxID: 147828;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-28 23:33:27	ID requested
1	2023-09-29 00:29:29	announced
⏵ 2	2023-11-14 08:55:06	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: Opisthorchis felineus, Proteomics, Secretome, Microvesicles (MVs), tegument

Javier Sotillo
contact affiliation	Instituto de Salud Carlos III
contact email	javier.sotillo@isciii.es
lab head
Javier Sotillo
contact affiliation	Instituto de Salud Carlos III
contact email	javier.sotillo@isciii.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD045798

PRIDE project URI

• PRIDE
  1. PXD045798
     1. Label: PRIDE project
     2. Name: Secreted and surface proteome and transcriptome of Opisthorchis felineus