PXD045698

PXD045698 is an original dataset announced via ProteomeXchange.

Title	LC-MS/MS analysis on in-vivo mice gastrointestinal digests
Description	Food protein amyloid fibrils have superior technological,nutritional,sensorial,and physical properties compared to native monomers, butthere is yet insufficient understanding of their digestive fate and safety for wide consumption.By combining SDS,ELISA,fluorenscence,AFM, MALDI-MS, CD microfluidics,and SAXS techniques for the characterization of blg and lysozyme amyloid fibrils subjected to in-vitro gastrointestinal digestion.LC-MS/MS analysis on the fate of blg/lysozyme amyloid fibrils digested in vivo by mice was applied to verify our in vitro results.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:13:42.369.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dan Xu
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-26 07:41:35	ID requested
1	2023-10-30 03:02:53	announced
⏵ 2	2023-11-14 09:13:44	announced	2023-11-14: Updated project metadata.

Xu D, Zhou J, Soon WL, Kutzli I, Moli, è, re A, Diedrich S, Radiom M, Handschin S, Li B, Li L, Sturla SJ, Ewald CY, Mezzenga R, Food amyloid fibrils are safe nutrition ingredients based on in-vitro and in-vivo assessment. Nat Commun, 14(1):6806(2023) [pubmed]

submitter keyword: mice intestinal colon serum LC-MS

Raffaele Mezzenga
contact affiliation	Department of Health Science & Technology & Department of Materials, ETH Zurich,Schmelzbergstrasse 9,LFO,E23,8092 Zurich,Switzerland
contact email	raffaele.mezzenga@hest.ethz.ch
lab head
Dan Xu
contact affiliation	School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, Engineering Research Center of Starch and Plant Protein Deep Processing, Ministry of Education, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou, 510640, China
contact email	danxu0913@outlook.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD045698

PRIDE project URI

• PRIDE
  1. PXD045698
     1. Label: PRIDE project
     2. Name: LC-MS/MS analysis on in-vivo mice gastrointestinal digests