PXD045681
PXD045681 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Study on the treatment of ITP mice with IVIG sourced from distinct sex-special plasma (DSP-IVIG) |
| Description | Intravenous immunoglobulin (IVIG) is a first-line drug prepared from human plasma for the treatment of autoimmune diseases (AID), especially immune thrombocytopenia (ITP). Since significant differences exist in protein types and expression levels between male and female plasma, and the prevalence of autoimmune diseases varies between sexes. The present study seeks to explore potential variations in IVIG sourced from distinct sex-specific plasma (DSP-IVIG), including IVIG sourced from female plasma (F-IVIG), IVIG sourced from male plasma (M-IVIG), and IVIG sourced from a blend of male and female plasma (Mix-IVIG). We investigate whether these IVIG variants exhibit different effects in the treatment of ITP. To address this question, we established an ITP mouse model treated with DSP IVIG. |
| HostingRepository | iProX |
| AnnounceDate | 2023-09-26 |
| AnnouncementXML | Submission_2023-12-04_20:57:17.370.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Wei Zhang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-09-25 19:49:09 | ID requested | |
| 1 | 2023-09-25 19:49:17 | announced | |
| ⏵ 2 | 2023-12-04 20:57:18 | announced | 2023-12-05: Update publication information. |
Publication List
| Zhang W, Yuan X, Wang Z, Xu J, Ye S, Jiang P, Du X, Liu F, Lin F, Zhang R, Ma L, Li C, Study on the Treatment of ITP Mice with IVIG Sourced from Distinct Sex-Special Plasma (DSP-IVIG). Int J Mol Sci, 24(21):(2023) [pubmed] |
Keyword List
| submitter keyword: DSP-IVIG, ITP |
Contact List
| Changqing Li | |
|---|---|
| contact affiliation | Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College |
| contact email | changqing.li@ibt.pumc.edu.cn |
| lab head | |
| Wei Zhang | |
| contact affiliation | Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College |
| contact email | 18581556966@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
