PXD045669

PXD045669 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mouse rod photoreceptor Prkaa2 knockout phosphoproteomics
Description	Mouse rod photoreceptors isolated from retinas of Prkaa2 rod photoreceptor specific knockout mice were processed for phosphoproteomics to elucidate downstream kinase targets. Prkaa2 is an isoform of the catalytic subunit of AMP-activated protein kinase (AMPK), an essential nutrient-sensing enzyme responsible for maintaining many metabolic processes.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:45:13.063.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tae Jun Lee
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-25 11:52:21	ID requested
1	2024-06-15 23:00:46	announced
⏵ 2	2024-10-22 06:45:15	announced	2024-10-22: Updated project metadata.

Publication List

10.1172/jci.insight.173707;
Lee TJ, Sasaki Y, Ruzycki PA, Ban N, Lin JB, Wu HT, Santeford A, Apte RS, Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function. JCI Insight, 9(4):(2024) [pubmed]

10.1172/jci.insight.173707;

Lee TJ, Sasaki Y, Ruzycki PA, Ban N, Lin JB, Wu HT, Santeford A, Apte RS, Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function. JCI Insight, 9(4):(2024) [pubmed]

Keyword List

submitter keyword: Mouse
rod photoreceptor
Prkaa2
AMPK
phosphoproteomics

submitter keyword: Mouse

rod photoreceptor

Prkaa2

AMPK

phosphoproteomics

Contact List

Rajendra Apte
contact affiliation	Washington University in St. Louis School of Medicine
contact email	apte@wustl.edu
lab head
Tae Jun Lee
contact affiliation	Washington University in St. Louis School of Medicine
contact email	t.lee@wustl.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD045669
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD045669

PRIDE project URI

Repository Record List

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