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PXD045667

PXD045667 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse rod photoreceptor Prkaa1 knockout phosphoproteomics
DescriptionMouse rod photoreceptor specific Prkaa1 knockouts were isolated from retinas and processed for phosphoproteomics to elucidate downstream kinase targets. Prkaa1 is one of the isoforms for the catalytic subunit of AMP-activated protein kinase (AMPK), an essential nutrient sensing enzyme responsible for maintaining many metabolic processes.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:45:06.438.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTae Jun Lee
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-25 11:36:07ID requested
12024-06-15 22:59:13announced
22024-10-22 06:45:07announced2024-10-22: Updated project metadata.
Publication List
10.1172/jci.insight.173707;
Lee TJ, Sasaki Y, Ruzycki PA, Ban N, Lin JB, Wu HT, Santeford A, Apte RS, Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function. JCI Insight, 9(4):(2024) [pubmed]
Keyword List
submitter keyword: Mouse, AMPK, rod photoreceptors, Prkaa1, phosphoproteomics
Contact List
Rajendra Apte
contact affiliationWashington University in St. Louis School of Medicine
contact emailapte@wustl.edu
lab head
Tae Jun Lee
contact affiliationWashington University in St. Louis School of Medicine
contact emailt.lee@wustl.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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