PXD045656

PXD045656 is an original dataset announced via ProteomeXchange.

Title	Whole-cell differential proteomics analysis of MG1655 Escherichia coli (Wild-type and mutants lacking the small regulatory RNA SdsR, OxyS or ZbiJ, or the RNA Chaperone Hfq) experiencing long-term nitrogen starvation in Gutnick minimal media.
Description	Proteomics was carried out to compare the proteomes of wild-type MG1655 E coli with mutants lacking either prominent sRNA, SdsR, OxyS or ZbiJ, or lacking the ubiquitous RNA chaperone proteins hfq, in bacteria that had been exposure to long-term (24hr) nitrogen starvation in Gutnick minimal media. The aim of this was to understand what the regulatory contribution of these three sRNA was to bacteria experiencing long-term nitrogen starvation.
HostingRepository	PRIDE
AnnounceDate	2024-05-24
AnnouncementXML	Submission_2024-05-24_01:03:26.695.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Josh McQuail
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-25 06:50:24	ID requested
⏵ 1	2024-05-24 01:03:27	announced

10.1093/nar/gkad1211;

McQuail J, Matera G, Gr, ä, fenhan T, Bischler T, Haberkant P, Stein F, Vogel J, Wigneshweraraj S, Hfq-mediated RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery. Nucleic Acids Res, 52(5):2323-2339(2024) [pubmed]

submitter keyword: zbij, hfq,E coli, oxys, nitrogen starvation, stationary phase, sdsr, srna

Sivaramesh Wigneshweraraj
contact affiliation	Department of Infectious Disease, Imperial College London
contact email	s.r.wig@imperial.ac.uk
lab head
Josh McQuail
contact affiliation	Department of Infectious Diseases, Imperial College London
contact email	jwm116@ic.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD045656

PRIDE project URI

• PRIDE
  1. PXD045656
     1. Label: PRIDE project
     2. Name: Whole-cell differential proteomics analysis of MG1655 Escherichia coli (Wild-type and mutants lacking the small regulatory RNA SdsR, OxyS or ZbiJ, or the RNA Chaperone Hfq) experiencing long-term nitrogen starvation in Gutnick minimal media.