PXD045567

PXD045567 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The epigenomic landscape of cognitive stimulation in the context of aging in mouse dorsal hippocampus - SWATH
Description	Aging is a universal biological phenomenon linked to many diseases, such as cancer or neurodegeneration. However, the molecular mechanisms underlying aging, or how lifestyle interventions such as cognitive stimulation can ameliorate this process, are yet to be clarified. Here, we performed a multi-omic profiling, including RNA-seq, ATAC-seq, ChIP-seq, EM-seq, SWATH-MS and single cell Multiome scRNA and scATAC-seq, in the dorsal hippocampus of young and old mouse subjects which were subject to cognitive stimulation using the paradigm of environmental enrichment. In this study we were able to describe the epigenomic landscape of aging and cognitive stimulation.
HostingRepository	PRIDE
AnnounceDate	2023-09-29
AnnouncementXML	Submission_2023-09-29_12:35:19.082.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	MarioFraga
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-21 10:57:42	ID requested
⏵ 1	2023-09-29 12:35:19	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: LC-MSMS,mouse, hippocampus, SWATH, rejuvenation, aging

submitter keyword: LC-MSMS,mouse, hippocampus, SWATH, rejuvenation, aging

Contact List

Mario FernandezFraga
contact affiliation	CSIC - Consejo Superior de Investigaciones Cientificas
contact email	mffraga@cinn.es
lab head
MarioFraga
contact affiliation	CSIC
contact email	epigeneticslabfinba@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD045567
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD045567

PRIDE project URI

Repository Record List

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