PXD045516

PXD045516 is an original dataset announced via ProteomeXchange.

Title	Data of mass spectrometry analysis of proteins interactingwith fibroblast activity protein in dysplastic oralkeratinocyte cells
Description	This project adopts mass spectrometry proteomics technology for research. The experiment was divided into four groups: the experimental group was D1 group, D2 group, and the control group was D3 group and D4 group(D2 is the repeating group of D1, and D4 is the repeating group of D3）. The experimental group and control group were treated with mouse monoclonal anti FAP antibodies (SC-100528; Santa Cruz Biotechnology, Dallas, TX, USA) and normal mouse IgG antibodies (A7028, Beyotime Biotechnology), respectively. A total of 700 proteins were identified in four samples, of which 290 were false positive proteins. The remaining 290 proteins were only positively expressed in the D1 group, 62 proteins were only expressed in the D2 group, and 121 proteins were both positively expressed in both D1 and D2 groups. Based on the above data, a systematic analysis was conducted on all identified proteins in combination with bioinformatics.
HostingRepository	iProX
AnnounceDate	2023-09-20
AnnouncementXML	Submission_2023-09-20_03:39:59.778.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tiantian Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-20 03:39:51	ID requested
⏵ 1	2023-09-20 03:40:00	announced

Dataset with its publication pending

submitter keyword: DOK(dysplastic oral keratinocyte), FAP(fibroblast activityprotein), MS(mass spectrometry analysis)

Ran Li
contact affiliation	Shanxi Medical University
contact email	lraner@163.com
lab head
Tiantian Liu
contact affiliation	Shanxi Medical University
contact email	2938109030@qq.com
dataset submitter

iProX dataset URI