⮝ Full datasets listing

PXD045506

PXD045506 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBranched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC
DescriptionImmunotherapy has revolutionized cancer treatment, however, a reliable biomarker is missing. MGAT5-mediated PD-L1 glycosylation is critical for its interaction with PD-1. MGAT5 expression is a functional biomarker that predicts immunotherapy responses.
HostingRepositoryPRIDE
AnnounceDate2025-05-06
AnnouncementXMLSubmission_2025-05-06_11:40:32.004.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD045506
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterHsin-Yi Wu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListN-glycosylated residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-19 22:55:44ID requested
12025-05-06 11:40:32announced
Publication List
Huang HC, Huang YL, Chen YJ, Wu HY, Hsu CL, Kao HF, Liao BC, Hsieh MS, Lin NY, Liao YH, Chen HL, Chen CN, Chen TC, Wang CP, Yang TL, Huang MC, Lin MC, Lou PJ, The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC. Oncogenesis, 13(1):36(2024) [pubmed]
10.6019/PXD045506;
10.1038/s41389-024-00532-3;
Keyword List
submitter keyword: MGAT5,Immunotherapy, N-glycosylation, PD-L1, Head and neck squamous cell carcinoma (HNSCC)
Contact List
Min-Chuan Huang
contact affiliationGraduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University. Taipei, Taiwan
contact emailmchuang@ntu.edu.tw
lab head
Hsin-Yi Wu
contact affiliationNational Taiwan University
contact emailclairewu.wu@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD045506
PRIDE project URI
Repository Record List
[ + ]