PXD045506 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC |
Description | Immunotherapy has revolutionized cancer treatment, however, a reliable biomarker is missing. MGAT5-mediated PD-L1 glycosylation is critical for its interaction with PD-1. MGAT5 expression is a functional biomarker that predicts immunotherapy responses. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-06 |
AnnouncementXML | Submission_2025-05-06_11:40:32.004.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD045506 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Hsin-Yi Wu |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | N-glycosylated residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-09-19 22:55:44 | ID requested | |
⏵ 1 | 2025-05-06 11:40:32 | announced | |
Publication List
Huang HC, Huang YL, Chen YJ, Wu HY, Hsu CL, Kao HF, Liao BC, Hsieh MS, Lin NY, Liao YH, Chen HL, Chen CN, Chen TC, Wang CP, Yang TL, Huang MC, Lin MC, Lou PJ, The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC. Oncogenesis, 13(1):36(2024) [pubmed] |
10.6019/PXD045506; |
10.1038/s41389-024-00532-3; |
Keyword List
submitter keyword: MGAT5,Immunotherapy, N-glycosylation, PD-L1, Head and neck squamous cell carcinoma (HNSCC) |
Contact List
Min-Chuan Huang |
contact affiliation | Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University. Taipei, Taiwan |
contact email | mchuang@ntu.edu.tw |
lab head | |
Hsin-Yi Wu |
contact affiliation | National Taiwan University |
contact email | clairewu.wu@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD045506 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD045506
- Label: PRIDE project
- Name: Branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC