PXD045488

PXD045488 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Glycosylation of somatic extracts and secretome in the infective stage of the helminth Fasciola hepatica
Description	Fasciola hepatica is a global helminth parasite of humans and their livestock. The invasive stage of the parasite, the newly excysted juvenile (NEJs), relies on glycosylated excretedsecreted (ES) products and surface/somatic molecules to interact with host cells and tissues and to evade the host's immune responses. Here, we employed glycoproteomic and proteomic analyses to determine the glycosylation profile of proteins within the NEJs’ somatic (Som) and ES extracts.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-26_07:04:07.593.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jonas Nilsson
SpeciesList	scientific name: Fasciola hepatica (Liver fluke); NCBI TaxID: 6192;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-19 06:41:38	ID requested
⏵ 1	2024-01-26 07:04:08	announced

Publication List

De Marco Verissimo C, Cwiklinski K, Nilsson J, Mirgorodskaya E, Jin C, Karlsson NG, Dalton JP, Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica. Mol Cell Proteomics, 22(12):100684(2023) [pubmed]
10.1016/j.mcpro.2023.100684;

De Marco Verissimo C, Cwiklinski K, Nilsson J, Mirgorodskaya E, Jin C, Karlsson NG, Dalton JP, Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica. Mol Cell Proteomics, 22(12):100684(2023) [pubmed]

10.1016/j.mcpro.2023.100684;

Keyword List

submitter keyword: glycoproteomics, orbitrap, Parasites,Glycosylation, LC-MS/MS

submitter keyword: glycoproteomics, orbitrap, Parasites,Glycosylation, LC-MS/MS

Contact List

John Dalton
contact affiliation	Molecular Parasitology Lab - Centre for One Health and Ryan Institute, School of Natural Science, National University of Ireland Galway, Galway, Republic of Ireland.
contact email	johnpius.dalton@universityofgalway.ie
lab head
Jonas Nilsson
contact affiliation	Proteomics Core Facility, University of Gothenburg
contact email	jonas.gm.nilsson@gu.se
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD045488
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD045488

PRIDE project URI

Repository Record List

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