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PXD045325

PXD045325 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic solubility changes induced by pathogenic human tau/MAPT during aging in Drosophila.
DescriptionAging and other proteostatic stresses can lead to accumulation of insoluble protein aggregates that disrupt normal cell function. We would like to identify these proteins accumulating in insoluble proteins fractions and better understand the molecular mechanisms of how these proteins accumulate.
HostingRepositoryPRIDE
AnnounceDate2024-09-30
AnnouncementXMLSubmission_2024-09-30_13:48:08.892.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterVishwajeeth Pagala
SpeciesList scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-12 13:51:09ID requested
12024-09-30 13:48:09announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: tau/MAPT
proteome insolubility
Drosophila melanogaster.
Contact List
Fabio Demontis
contact affiliationAssociate Member, Developmental Neurobiology St. Jude Children's Research hosptial
contact emailfabio.demontis@stjude.org
lab head
Vishwajeeth Pagala
contact affiliationSt. Jude Children's Research Hospital
contact emailvishwajeeth.pagala@stjude.org
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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