PXD045261

PXD045261 is an original dataset announced via ProteomeXchange.

Title	Characterisation of vestibular schwannoma tissues using LC-MS/MS analysis
Description	Vestibular schwannoma is the most common benign neoplasm of the cerebellopontine angle. Its first symptoms include hearing loss, tinnitus, and vestibular symptoms, followed by cerebellar and brainstem symptoms, along with palsy of the adjacent cranial nerves. However, the clinical picture has unpredictable dynamics and currently, there are no reliable predictors of tumour behaviour. The major objective of this study was to verify whether a technique using in-sample specific protein digestion with trypsin would have the potential to provide proteomic characterisation of these pathological tissues.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:15:30.248.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiri Santrucek
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-11 04:19:06	ID requested
1	2023-09-26 03:45:07	announced
⏵ 2	2023-11-14 08:15:30	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: liquid chromatography,in-sample protein digestion, tandem mass spectrometry, vestibular schwannomas, principal component analysis

Radovan Hynek
contact affiliation	Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague
contact email	hynekr@vscht.cz
lab head
Jiri Santrucek
contact affiliation	University of Chemistry and Technology Prague
contact email	santrucj@vscht.cz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD045261

PRIDE project URI

• PRIDE
  1. PXD045261
     1. Label: PRIDE project
     2. Name: Characterisation of vestibular schwannoma tissues using LC-MS/MS analysis