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PXD045206

PXD045206 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification and validation of differential proteins in liver tissues of New Zealand rabbits at different months of age
DescriptionRabbit hemorrhagic disease is an acute and highly fatal infectious disease caused by rabbit hemorrhagic disease virus. The mortality rate of adult rabbits is more than 90 %, but 2-week-old young rabbits are not affected. Based on the differences in the susceptibility of young rabbits and adult rabbits to RHDV, TMT proteomics technology was used to detect and quantitatively analyze the liver tissue proteins of young rabbits (2 weeks old) and adult rabbits (6 months old). 4353 proteins were quantitatively obtained from the liver tissues of young rabbits and adult rabbits, and 821 differential proteins were screened. Among them, 294 proteins were significantly upregul-ated and 527 proteins were significantly down-regulated in the liver tissues of adult rabbits compared with young rabbits.
HostingRepositoryiProX
AnnounceDate2022-11-30
AnnouncementXMLSubmission_2023-09-07_20:14:50.082.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQiongyi Li
SpeciesList scientific name: Oryctolagus cuniculus; NCBI TaxID: 9986;
ModificationListTMT6plex reporter fragment
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-07 20:14:34ID requested
12023-09-07 20:14:50announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: New Zealand rabbit, TMT proteomics, Bioinformatics, Liver, Differential proteins
Contact List
Jialin Bai
contact affiliationBiomedical Research Center, Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Northwest Minzu University, Lanzhou, China
contact emailjlbai@xbmu.edu.cn
lab head
Qiongyi Li
contact affiliationBiomedical Research Center, Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Northwest Minzu University, Lanzhou, China
contact emaillqy@xbmu.edu.cn
dataset submitter
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iProX dataset URI