PXD045096
PXD045096 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TAK1 is an essential kinase for STING trafficking |
| Description | STING-mediated activation of TAK1 at the ER, which in turn induces STING phosphorylation and initiates STEEP-mediated STING trafficking. These findings shed light on an early signaling event in the regulation of STING exit from ER. |
| HostingRepository | iProX |
| AnnounceDate | 2023-09-05 |
| AnnouncementXML | Submission_2024-05-22_19:56:28.942.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Mingtong Ma |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | phosphorylated residue |
| Instrument | LTQ |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-09-04 22:23:56 | ID requested | |
| 1 | 2023-09-04 22:24:44 | announced | |
| ⏵ 2 | 2024-05-22 19:56:29 | announced | 2024-05-23: Update information. |
Publication List
| Ma M, Dang Y, Chang B, Wang F, Xu J, Chen L, Su H, Li J, Ge B, Chen C, Liu H, TAK1 is an essential kinase for STING trafficking. Mol Cell, 83(21):3885-3903.e5(2023) [pubmed] |
Keyword List
| submitter keyword: stimulator of interferon genes, transforming growth factor beta-activated kinase 1, phosphorylation, trafficking, immunotherapy |
Contact List
| Haipeng Liu | |
|---|---|
| contact affiliation | Tongji University |
| contact email | haipengliu@tongji.edu.cn |
| lab head | |
| Mingtong Ma | |
| contact affiliation | Tongji University |
| contact email | mingtongma@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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