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PXD045083

PXD045083 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIntegrated proteogenomic analysis of outer membrane vesicles from hypervirulent Klebsiella pneumoniae
DescriptionHypervirulent Klebsiella pneumoniae (hvKp) causes invasive infections and severe systemic inflammation. In this study, outer membrane vesicles (OMVs) derived from clinically isolated hvKp and classical K. pneumoniae (cKp) strains were characterized using an integrated proteogenomic workflow combining whole-genome sequencing and label-free LC–MS/MS proteomics. The dataset includes quantitative proteomic profiles of OMVs and whole-cell lysates together with strain-specific protein annotations for comparative analyses of OMVs cargo composition, functional annotation, and pathogenicity.
HostingRepositoryPRIDE
AnnounceDate2026-07-22
AnnouncementXMLSubmission_2026-07-22_06:19:44.697.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJing Chen
SpeciesList scientific name: Klebsiella pneumoniae; NCBI TaxID: NEWT:573; scientific name: Bacteria; NCBI TaxID: NCBITaxon:2;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-04 07:19:52ID requested
12026-07-22 06:19:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Outer membrane vesicles,Klebsiella pneumoniae
Contact List
Jing Chen
contact affiliationDepartment of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, People's Republic of China.
contact emaildongqingfei@126.com
lab head
Jing Chen
contact affiliationDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University
contact emaildongqingfei@126.com
dataset submitter
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Dataset FTP location
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