PXD045069

PXD045069 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human liver cell line LO2 LC-MS/MS
Description	A hyperlipidaemia model of L02 cells was established using free fatty acids (FFA, oleate and palmitate, 2:1; Sigma-Aldrich, USA) at a final concentration of 1 mM for 24 h. Cells were allowed to attach overnight prior to HTG-medicated serum for 24 h and then exposed to FFA during drug treatment. After treatment, LO2 cells were harvest and stored at -80 ℃, lactylation proteomics was performed by Jingjie PTM BioLabs (Hangzhou, China).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:25:09.217.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Li Min
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	lactic acid
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-03 23:42:45	ID requested
1	2024-01-26 06:16:40	announced
⏵ 2	2024-10-22 06:25:11	announced	2024-10-22: Updated project metadata.

Publication List

Yin X, Li M, Wang Y, Zhao G, Yang T, Zhang Y, Guo J, Meng T, Du R, Li H, Wang Z, Zhang J, He Q, Herbal medicine formula Huazhuo Tiaozhi granule ameliorates dyslipidaemia via regulating histone lactylation and miR-155-5p biogenesis. Clin Epigenetics, 15(1):175(2023) [pubmed]
10.1186/s13148-023-01573-y;

Yin X, Li M, Wang Y, Zhao G, Yang T, Zhang Y, Guo J, Meng T, Du R, Li H, Wang Z, Zhang J, He Q, Herbal medicine formula Huazhuo Tiaozhi granule ameliorates dyslipidaemia via regulating histone lactylation and miR-155-5p biogenesis. Clin Epigenetics, 15(1):175(2023) [pubmed]

10.1186/s13148-023-01573-y;

Keyword List

submitter keyword: Human, liver cell, LC-MS/MS

submitter keyword: Human, liver cell, LC-MS/MS

Contact List

Qingyong He
contact affiliation	Guang'anmen Hospital of China Academy of Chinese Medical Sciences
contact email	heqingyongg@163.com
lab head
Li Min
contact affiliation	China Academy of Chinese Medical Sciences
contact email	limione0101@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD045069
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD045069

PRIDE project URI

Repository Record List

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