PXD045045

PXD045045 is an original dataset announced via ProteomeXchange.

Title	LC-MS of Human Blood of Pancreatic neuroendocrine tumors
Description	Pancreatic Neuroendocrine tumors are challenging to diagnose and often detected at advanced stages due to lack of specific and sensitive biomarkers. This study utilized proteomics as a valuable approach for cancer biomarker discovery, therefore, mass spectrometry-based proteomic profiling was conducted on plasma samples from 12 subjects (3 controls; 9 PanNET patients) to identify potential proteins capable of effectively distinguish PanNET from healthy controls. 13.2% of proteins were uniquely identified in PanNET, while 60% were commonly expressed in PanNET and controls. 17 proteins exhibiting significant differential expression between PanNET and controls were identified with downstream analysis.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-26_07:03:27.598.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Priya Kumari Gorai
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-01 22:40:30	ID requested
⏵ 1	2024-01-26 07:03:28	announced

10.1038/s41598-023-48323-x;

Gorai PK, Bharti PS, Kumar S, Rajacharya GH, Bandyopadhyay S, Pal S, Dhingra R, Kumar R, Nikolajeff F, Kumar S, Rani N, C1QA and COMP: plasma-based biomarkers for early diagnosis of pancreatic neuroendocrine tumors. Sci Rep, 13(1):21021(2023) [pubmed]

submitter keyword: Human, Pancreatic neuroendocrine tumors, LC-MS, Plasma

Neerja Rani
contact affiliation	Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India
contact email	neerja.sirohi@gmail.com
lab head
Priya Kumari Gorai
contact affiliation	All India Institute of Medical Sciences, New Delhi
contact email	deepupriya003@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD045045

PRIDE project URI

• PRIDE
  1. PXD045045
     1. Label: PRIDE project
     2. Name: LC-MS of Human Blood of Pancreatic neuroendocrine tumors