PXD044986

PXD044986 is an original dataset announced via ProteomeXchange.

Title	Diversity of post-translational modifications and signaling networks revealed by single cell and organelle mass spectrometry
Description	Using an optimized data-independent acquisition approach on trapped ion mobility spectrometry, we measured proteins, post-translational modifications and variant peptides in single cells and single nuclei, which provided insights into heterogeneity of cell-state and signaling dependencies at the single cell level and the molecular impact of an epigenetic drug at the level of a single organelle.
HostingRepository	PRIDE
AnnounceDate	2024-08-02
AnnouncementXML	Submission_2024-08-02_01:38:27.429.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Akhilesh Pandey
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; phosphorylated residue; acetylated residue
Instrument	timsTOF SCP

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-31 00:19:57	ID requested
⏵ 1	2024-08-02 01:38:28	announced

10.1038/s42003-024-06579-7;

Mun DG, Bhat FA, Joshi N, Sandoval L, Ding H, Jain A, Peterson JA, Kang T, Pujari GP, Tomlinson JL, Budhraja R, Zenka RM, Kannan N, Kipp BR, Dasari S, Gaspar-Maia A, Smoot RL, Kandasamy RK, Pandey A, Diversity of post-translational modifications and cell signaling revealed by single cell and single organelle mass spectrometry. Commun Biol, 7(1):884(2024) [pubmed]

submitter keyword: LC-MS,Single cell, diaPASEF, Proteomics

Akhilesh Pandey
contact affiliation	Mayo Clinic, Rochester, USA
contact email	Pandey.Akhilesh@mayo.edu
lab head
Akhilesh Pandey
contact affiliation	Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905
contact email	pandey.akhilesh@mayo.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044986

PRIDE project URI

• PRIDE
  1. PXD044986
     1. Label: PRIDE project
     2. Name: Diversity of post-translational modifications and signaling networks revealed by single cell and organelle mass spectrometry