PXD044919

PXD044919 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of Lysine lactylation in adipose tissue of HIIT mice
Description	This project carried out a quantitative study of the target proteins that are lactylated and regulated by lactate levels in iWAT of HIIT mice. In order to ensure a high degree of credibility of the results, we quantitatively analyzed the changes in protein lactylation in three groups. Modification sites in both groups with p <0.05 were considered significantly different modifications, and the standard for up- or down-regulated modification sites was set as a fold change >1.3 or <0.7, respectively. In this study, We identified 602 quantifiable sites and 217 quantifiable proteins. Subsequently, we carried out a systematic bioinformatics analysis of proteins containing quantitative information sites, including protein annotation, functional classification, functional enrichment and cluster analysis based on functional enrichment.
HostingRepository	iProX
AnnounceDate	2023-08-29
AnnouncementXML	Submission_2024-02-19_19:45:18.753.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jing Zhang
SpeciesList	scientific name: Mus ; NCBI TaxID: 10088;
ModificationList	lactic acid
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-28 20:26:11	ID requested
1	2023-08-28 20:26:32	announced
2	2023-12-04 21:09:49	announced	2023-12-05: Update publication information.
⏵ 3	2024-02-19 19:45:19	announced	2023-12-05: Update publication information. 2024-02-20: Update information.

submitter keyword: High-intensity interval training, Lactylation, Fatty acid synthase, Fat loss

Jing Zhang
contact affiliation	Beijing Normal University
contact email	zhangjing@bnu.edu.cn
lab head
Jing Zhang
contact affiliation	Beijing Normal University
contact email	zhangjing@bnu.edu.cn
dataset submitter

iProX dataset URI