PXD044919
PXD044919 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Analysis of Lysine lactylation in adipose tissue of HIIT mice |
| Description | This project carried out a quantitative study of the target proteins that are lactylated and regulated by lactate levels in iWAT of HIIT mice. In order to ensure a high degree of credibility of the results, we quantitatively analyzed the changes in protein lactylation in three groups. Modification sites in both groups with p <0.05 were considered significantly different modifications, and the standard for up- or down-regulated modification sites was set as a fold change >1.3 or <0.7, respectively. In this study, We identified 602 quantifiable sites and 217 quantifiable proteins. Subsequently, we carried out a systematic bioinformatics analysis of proteins containing quantitative information sites, including protein annotation, functional classification, functional enrichment and cluster analysis based on functional enrichment. |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-29 |
| AnnouncementXML | Submission_2024-02-19_19:45:18.753.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jing Zhang |
| SpeciesList | scientific name: Mus |
| ModificationList | lactic acid |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-28 20:26:11 | ID requested | |
| 1 | 2023-08-28 20:26:32 | announced | |
| 2 | 2023-12-04 21:09:49 | announced | 2023-12-05: Update publication information. |
| ⏵ 3 | 2024-02-19 19:45:19 | announced | 2023-12-05: Update publication information. 2024-02-20: Update information. |
Publication List
| Chen X, Huang W, Zhang J, Li Y, Xing Z, Guo L, Jiang H, Zhang J, High-intensity interval training induces lactylation of fatty acid synthase to inhibit lipid synthesis. BMC Biol, 21(1):196(2023) [pubmed] |
Keyword List
| submitter keyword: High-intensity interval training, Lactylation, Fatty acid synthase, Fat loss |
Contact List
| Jing Zhang | |
|---|---|
| contact affiliation | Beijing Normal University |
| contact email | zhangjing@bnu.edu.cn |
| lab head | |
| Jing Zhang | |
| contact affiliation | Beijing Normal University |
| contact email | zhangjing@bnu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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