PXD044877

PXD044877 is an original dataset announced via ProteomeXchange.

Title	Protein profiling of bovine colostrum and transition milk
Description	The protein profile of bovine milk serum was characterised as milk transitions from colostrum to transition milk over the first 5 days of lactation. Samples were collected from first and third parity cows at days 0, 2, 5 (D0, D2, D5) after calving. Following isolation of the milk serum fraction, label-free quantitative proteomics was carried out following normalisation by total protein concentration. Protein profiles indicated samples clustered by day postpartum, but not by parity. Proteins (n = 471) were identified and relative quantification was performed, with 199 protein groups showing altered abundance by day of lactation (fold change ≥ 2, P < 0.05). Elevated levels of immune proteins, including immunoglobulins and complement proteins were detected in colostrum with levels significantly decreasing by D2. These findings provide an outline of the dynamics of the protein profile of bovine milk and colostrum in early lactation.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:58:30.896.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rebecca Owens
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-26 04:03:14	ID requested
1	2023-09-25 03:56:10	announced
⏵ 2	2023-11-14 07:58:31	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: Q-Exactive, milk serum, label-free proteomics, colostrum,Milk

Rebecca A.
contact affiliation	Department of Biology, Maynooth University, Ireland
contact email	rebecca.owens@mu.ie
lab head
Rebecca Owens
contact affiliation	Maynooth University
contact email	rebecca.owens@mu.ie
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD044877

PRIDE project URI

• PRIDE
  1. PXD044877
     1. Label: PRIDE project
     2. Name: Protein profiling of bovine colostrum and transition milk