PXD044845

PXD044845 is an original dataset announced via ProteomeXchange.

Title	Eye proteome of Drosophila melanogaster
Description	We report the proteome composition of the Drosophila eye – a compound organ that is highly enriched in membrane proteins. The fly eye is a popular model to study the physiology of vision by means of genetic, pharmacological, and dietary interference.While the eye transcriptome and development-related changes of gene expression profiles have been extensively studied, little is known about the eye proteome.we employed GeLC-MS/MS to identify and rank the abundances of 3516 eye proteins. Moreover, we applied our MS Western method to determine the absolute (molar) abundances of a related set of proteins that are important for photoreceptor structure (including maintenance) and function (phototransduction). Altogether, we provide a comprehensive and expandable proteomics resource that will be valuable for a variety of studies of ocular biochemistry, physiology, and development.
HostingRepository	PRIDE
AnnounceDate	2024-08-09
AnnouncementXML	Submission_2024-08-09_03:20:45.358.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mukesh Kumar
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-25 00:54:54	ID requested
⏵ 1	2024-08-09 03:20:46	announced

10.1002/pmic.202300330;

Kumar M, Has C, Lam-Kamath K, Ayciriex S, Dewett D, Bashir M, Poupault C, Schuhmann K, Thomas H, Knittelfelder O, Raghuraman BK, Ahrends R, Rister J, Shevchenko A, Eye proteome of Drosophila melanogaster. Proteomics, 24(10):e2300330(2024) [pubmed]

submitter keyword: Eye, GeLC-MS/MS, Proteomics, Drosophila melanogaster

Andrej Shevchenko
contact affiliation	Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
contact email	shevchenko@mpi-cbg.de
lab head
Mukesh Kumar
contact affiliation	Cell Signaling Technology
contact email	mukeshbiot@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044845

PRIDE project URI

• PRIDE
  1. PXD044845
     1. Label: PRIDE project
     2. Name: Eye proteome of Drosophila melanogaster