PXD044845 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Eye proteome of Drosophila melanogaster |
Description | We report the proteome composition of the Drosophila eye – a compound organ that is highly enriched in membrane proteins. The fly eye is a popular model to study the physiology of vision by means of genetic, pharmacological, and dietary interference.While the eye transcriptome and development-related changes of gene expression profiles have been extensively studied, little is known about the eye proteome.we employed GeLC-MS/MS to identify and rank the abundances of 3516 eye proteins. Moreover, we applied our MS Western method to determine the absolute (molar) abundances of a related set of proteins that are important for photoreceptor structure (including maintenance) and function (phototransduction). Altogether, we provide a comprehensive and expandable proteomics resource that will be valuable for a variety of studies of ocular biochemistry, physiology, and development. |
HostingRepository | PRIDE |
AnnounceDate | 2024-08-09 |
AnnouncementXML | Submission_2024-08-09_03:20:45.358.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mukesh Kumar |
SpeciesList | scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-08-25 00:54:54 | ID requested | |
⏵ 1 | 2024-08-09 03:20:46 | announced | |
Publication List
10.1002/pmic.202300330; |
Kumar M, Has C, Lam-Kamath K, Ayciriex S, Dewett D, Bashir M, Poupault C, Schuhmann K, Thomas H, Knittelfelder O, Raghuraman BK, Ahrends R, Rister J, Shevchenko A, Eye proteome of Drosophila melanogaster. Proteomics, 24(10):e2300330(2024) [pubmed] |
Keyword List
submitter keyword: Eye, GeLC-MS/MS, Proteomics, Drosophila melanogaster |
Contact List
Andrej Shevchenko |
contact affiliation | Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany |
contact email | shevchenko@mpi-cbg.de |
lab head | |
Mukesh Kumar |
contact affiliation | Cell Signaling Technology |
contact email | mukeshbiot@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044845 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044845
- Label: PRIDE project
- Name: Eye proteome of Drosophila melanogaster