PXD044813
PXD044813 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | TOC1 and PRR5 as regulators of temperature compensation in the Arabidopsis circadian clock (12˚C vs 28˚C) |
Description | Ambient temperature potentially affects all biological systems. However, the period length of circadian clocks is close to 24 h over a broad range of physiological temperatures, known as temperature compensation. The mechanism underpinning the temperature compensation remains largely unknown. Here, we show that inhibitors of time progression, TIMING OF CAB EXPRESSION 1 (TOC1) and PSEUDO-RESPONSE REGULATOR 5 (PRR5) proteins, are required for the temperature compensation in Arabidopsis thaliana (Arabidopsis). Compared to the wild-type, the prr5 toc1 double mutant shows a short period at high temperatures. TOC1 and PRR5 proteins are ubiquitinated and degraded at low temperatures, by a ubiquitin E3 ligase LOV KELCH PROTEIN 2 (LKP2) that was sought as a minor player in the clock. The lkp2 mutants show long periods only at lower temperatures. Collectively, the clock keeps its periodicity against ambient temperature by the temperature-dependent quantity control of inhibitors of time progression. DOI:10.1126/sciadv.adq0187 |
HostingRepository | jPOST |
AnnounceDate | 2024-10-04 |
AnnouncementXML | Submission_2024-10-03_08:00:05.922.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD044813 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Norihito Nakamichi |
SpeciesList | scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702; |
ModificationList | unknown modification |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-08-23 18:39:57 | ID requested | |
⏵ 1 | 2024-10-03 08:00:06 | announced |
Publication List
Maeda AE, Matsuo H, Muranaka T, Nakamichi N, circadian clock. Sci Adv, 10(39):eadq0187(2024) [pubmed] |
Keyword List
submitter keyword: TOC1, PRR5, Arabidopsis, circadian clock, temperature |
Contact List
Norihito Nakamichi | |
---|---|
lab head | |
Norihito Nakamichi | |
contact affiliation | Nagoya University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002303/ |