PXD044805

PXD044805 is an original dataset announced via ProteomeXchange.

Title	Characterisation of proteomic alterations in worker bees in response to amitraz treatment during summer to winter transition in Apis mellifera colonies
Description	The application of treatments to reduce/control the number of Varroa destructor mites within in Apis mellifera colonies is common practice in apiculture. The effectiveness of the treatments in reducing/removing Varroa mites from colonies has been extensively studied, however, the effects of the treatments on the bees within the colonies is lacking. This work utilises proteomics to investigate how the presence of Apivar® strips within hives effects the worker bees. Samples of A. mellifera were isolated from colonies one week before Apivar® treatment and were sampled for 1, 3, 6 and 8 weeks post-treatment application. The results highlight two large proteomic shifts in workers between Control and Week 1 samples in comparison to Weeks 3, 6 and 8 samples. Cuticular proteins were decreased in abundance and translational proteins were increased in abundance in Weeks 3, 6 and 8 in comparison to Control and Week 1 samples. The proteomic shift in Week 8 in comparison to the other treatment samples was not as intense, with a lower number of increased translational proteins, indicating a reduction of treatment effect the longer it is within the hive. The work provides an initial insight into the effects Apivar® has on the honeybee population and how it may contribute to a stressful hive environment to a colony previously infested with Varroa mites.
HostingRepository	PRIDE
AnnounceDate	2025-07-01
AnnouncementXML	Submission_2025-07-01_06:16:56.567.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rachel Ward
SpeciesList	scientific name: Apis mellifera (Honeybee); NCBI TaxID: 7460;
ModificationList	monohydroxylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-23 10:23:11	ID requested
⏵ 1	2025-07-01 06:16:56	announced

10.1080/00218839.2024.2423133;

submitter keyword: Apis mellifera, translaition proteins, treatment response, cuticular proteins, anti-Varroa treatments, Proteomic Comparison

Kevin Kavanagh
contact affiliation	Lab head
contact email	kevin.kavanagh@mu.ie
lab head
Rachel Ward
contact affiliation	Teagasc
contact email	rachel.ward.2015@mumail.ie
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD044805
     1. Label: PRIDE project
     2. Name: Characterisation of proteomic alterations in worker bees in response to amitraz treatment during summer to winter transition in Apis mellifera colonies