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PXD044768

PXD044768 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleVPBrowse, genome-based representation of MS/MS spectra to quantify 10,000 bovine proteins
DescriptionSWATH is a mass spectrometry data acquisition strategy that relies on peptide spectral libraries to perform quantitatively accurate and consistent measurement of proteins across multiple samples. Public libraries have been developed for humans and several laboratory species that have accelerated biomarker discovery, and similarly comprehensive resources would be useful for other species. The Veterinary Proteome Browser, VPBrowse (http://browser.proteo.cloud/), is an on-line platform developed for genome-based representation of the Bos taurus proteome and is equipped with an interactive database and tools for visualization and building quantitative mass spectrometry assays. VPBrowse contains high quality tandem mass spectrometry (MS/MS) spectra acquired on QToF instrument for over 36,000 proteotypic peptides corresponding to over 10,000 bovine proteins. Data can be downloaded in different formats to enable analysis using popular software packages for SWATH data processing whilst normalization to iRT scale ensures compatibility with diverse chromatography systems. When applied to 25 different tissues and body fluids, the resource supported label-free quantification of nearly 30% of the protein-coding genes annotated in bovine section of UniprotKB.
HostingRepositoryPRIDE
AnnounceDate2024-03-07
AnnouncementXMLSubmission_2024-03-07_11:17:53.851.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPawel Sadowski
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-23 01:41:56ID requested
12024-03-07 11:17:54announced
Publication List
10.1002/PMIC.202300431;
Keyword List
submitter keyword: peptide spectral library,cattle, DDA data
Contact List
Pawel Sadowski
contact affiliationQueensland University of Technology
contact emailpawel.sadowski@qut.edu.au
lab head
Pawel Sadowski
contact affiliationQUT
contact emailpawel.sadowski@qut.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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