PXD044730

PXD044730 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Protemic characterisation of the β-thalassemia erythroid cells from immortalised cell lines
Description	β-thalassemia cell lines were generated via CRISPR-Cas9 genome editing of Bristol Erythroid Line Adult (BEL-A) and differentiated to the basophilic and polychromatic erythroid cell stage. TMT comparative proteomics was then performed on stage matched WT and β-thalassemia cells isolated by FACS.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:07:06.452.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Debbie Daniels
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-22 03:33:12	ID requested
1	2023-10-24 11:12:53	announced
⏵ 2	2023-11-14 09:07:11	announced	2023-11-14: Updated project metadata.

Publication List

Daniels DE, Ferrer-Vicens I, Hawksworth J, Andrienko TN, Finnie EM, Bretherton NS, Ferguson DCJ, Oliveira ASF, Szeto JA, Wilson MC, Brewin JN, Frayne J, -thalassemia enable in-depth analysis of disease phenotype. Nat Commun, 14(1):6260(2023) [pubmed]

Daniels DE, Ferrer-Vicens I, Hawksworth J, Andrienko TN, Finnie EM, Bretherton NS, Ferguson DCJ, Oliveira ASF, Szeto JA, Wilson MC, Brewin JN, Frayne J, -thalassemia enable in-depth analysis of disease phenotype. Nat Commun, 14(1):6260(2023) [pubmed]

Keyword List

submitter keyword: β-thalassemia erythroid cells

submitter keyword: β-thalassemia erythroid cells

Contact List

Jan Frayne
contact affiliation	School of Biochemistry, University of Bristol
contact email	Jan.Frayne@bristol.ac.uk
lab head
Debbie Daniels
contact affiliation	University of Bristol
contact email	debbie.daniels@bristol.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD044730
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD044730

PRIDE project URI

Repository Record List

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