PXD044643 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Targeted RNase H-mediated Extraction of crosslinked RBPs (TREX) for assessing U1 RNA interactome |
Description | We used Targeted RNase H-mediated Extraction of crosslinked RBPs (TREX)to assess the endogenous binding partners of U1 small nuclear RNA (U1 snRNA) in human HCT116 cells. Extracted proteins from U1 digested and control cells (5 replicate per condition) were compared, using label-free (LFQ) Quantitative proteomics. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:18:39.438.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Faraz Mardakheh |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-08-18 08:36:08 | ID requested | |
1 | 2023-12-27 08:18:39 | announced | |
⏵ 2 | 2024-10-22 06:18:39 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
submitter keyword: TREX |
RBP |
RNA Interactome |
LC-MS/MS |
Quantitative proteomics |
Contact List
Faraz Mardakheh |
contact affiliation | Centre for Cancer Cell & Molecular Biology Barts Cancer Institute Queen Mary University of London Charterhouse Square London EC1M 6BQ U.K. |
contact email | f.mardakheh@qmul.ac.uk |
lab head | |
Faraz Mardakheh |
contact affiliation | Barts Cancer Institute |
contact email | f.mardakheh@qmul.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044643
- Label: PRIDE project
- Name: Targeted RNase H-mediated Extraction of crosslinked RBPs (TREX) for assessing U1 RNA interactome