PXD044609

PXD044609 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Changes in the astronaut serum proteome during prolonged spaceflight
Description	The molecular mechanisms associated with spaceflight-induced biological adaptations that may affect many healthy tissue functions remain poorly understood. In this study, we analyzed temporal changes in the serum proteome of six astronauts during prolonged spaceflight missions using quantitative comprehensive proteome analysis performed with the data-independent acquisition method of mass spectrometry (DIA-MS). DIA-MS successfully identified 624 non-redundant proteins in sera and further quantitative analysis for each sampling point provided information on serum protein profiles closely related to several time points before (Pre-), during (In-), and after (Post-) spaceflight.
HostingRepository	jPOST
AnnounceDate	2024-01-22
AnnouncementXML	Submission_2024-01-21_23:17:36.503.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yayoi Kimura
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	unknown modification; alpha-amino acetylated residue; L-methionine sulfoxide; S-carboxamidomethyl-L-cysteine; alpha-aminocarbamoylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-17 10:23:23	ID requested
⏵ 1	2024-01-21 23:17:37	announced

Publication List

Kimura Y, Nakai Y, Ino Y, Akiyama T, Moriyama K, Aiba T, Ohira T, Egashira K, Yamamoto Y, Takeda Y, Inaba Y, Ryo A, Saito T, Kumagai K, Hirano H, Changes in the astronaut serum proteome during prolonged spaceflight. Proteomics, ():e2300328(2024) [pubmed]

Kimura Y, Nakai Y, Ino Y, Akiyama T, Moriyama K, Aiba T, Ohira T, Egashira K, Yamamoto Y, Takeda Y, Inaba Y, Ryo A, Saito T, Kumagai K, Hirano H, Changes in the astronaut serum proteome during prolonged spaceflight. Proteomics, ():e2300328(2024) [pubmed]

Keyword List

submitter keyword: Astronaut, Human serum, Mass spectrometry, Proteomics, Spaceflight

submitter keyword: Astronaut, Human serum, Mass spectrometry, Proteomics, Spaceflight

Contact List

Yayoi Kimura
lab head
Yayoi Kimura
contact affiliation	Yokohama City University
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002297/